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ZyGEM is a world leader in identifying and commercializing novel enzymes from extremophiles—microorganisms that exist in extreme environments around the globe. These enzymes have a multitude of current and potential applications in science and industry. ZyGEM’s internal and external research team includes individuals who have many decades of expertise in extremophiles and who are recognized leaders in the field. Central to the company’s core technology and product development efforts is the ZyGEM Culture Collection, a proprietary selection of 2000 microbial cultures isolated from a variety of locations worldwide.
ZyGEM currently offers two product families developed from its proprietary enzymes: prepGEM™ and forensicGEM™. These innovative products for DNA extraction and detection are available in a wide variety of formats for specific applications and provide important benefits to our customers, including increased speed, yield and accuracy at a lower cost.
In addition, over the past year ZyGEM has developed and acquired two new innovative technologies, microbial fingerprinting and isothermal DNA amplification, that provide a natural fit with the core DNA-extraction products and represent major new market opportunities.
By combining its patented reagent technologies with the “Lab-on-a-Chip” platform, ZyGEM has created a fully-integrated Micro-fluidic Chip platform (hardware plus reagent consumables). Management and partners believe this platform will transform the current DNA market, in part because it combines three currently-employed techniques onto a single, small and easy-to-use device. The ZyGEM “MicroLab” (Bench-top) platform starts as a bench-top version, with a vision for moving to a laptop-sized portable unit and, ultimately, a PDA-sized device over a five year period (with development funded largely by strategic partners for specific applications and markets).
ZyGEM’s technology and product portfolio is built around more than 20 years of research and development investment in its exclusive collection of more than 2000 microorganisms from extreme environments, including rare thermophilic organisms, as well as hundreds of characterized and documented enzymes.
ZyGEM’s proprietary thermophilic-derived EA1 enzyme formed the basis for the company’s patented forensicGEM™ and prepGEM™series of DNA extraction and detection kits, which were among the first products developed and commercialized from ZyGEM’s culture collections.
ZyGEM’s process based on these thermophilic enzymes extracts DNA using a unique single, closed-tube cycling process. This innovative technology has major competitive advantages over existing and historical methods. The benefits are significant and include:
ZyGEM’s laboratory products for DNA extraction and analysis meet or exceed all applicable manufacturing, safety and regulatory requirements, and our facility has been certified for production.