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Polymerase Chain Reaction (PCR) is the most common method for in vitro DNA amplification. This method requires thermocycling, increasing and decreasing the temperature, in order to separate the DNA strands for replication. An isothermal, or one temperature, method of DNA amplification would provide for a more simplified, more portable method of DNA replication which could potentially be used in the field or at the point-of-care.
ZyGEM has reached the pre-commercial development stage using its own proprietary isothermal methods that are novel and covered by a international patent applications. Commercialization of this promising technology will allow the company to expand into multiple major markets, as a replacement platform to historical PCR applications as well targeting specific diagnostic applications.