ZyGEM technology allows for simple, rapid, non-invasive DNA sample extraction by non-specialist staff in the hospital or clinic environment

APPLICATIONS: CLINICAL

ZyGEM's technology enables high throughput buccal cell or blood sample preparation for routine PCR-based genotyping for clinical or diagnostic applications, an approach that previously was unattainable or unaffordable.

For most genetic assays, end point or quantitative PCR assays are used; technologies that require minimal amounts of template. The closed tube capability of ZyGEM technology allows simple, rapid, non-invasive DNA sample extraction by non-specialist staff in the hospital or clinic environment, allowing low-cost screening with a very fast turnaround, and greater sensitivity than many other high throughput methods.

The high specific activity of forensicGEM is also applicable to single cell pre-genetic implantation diagnostics, significantly increasing the robustness of the assay. With a single template present, the value of comprehensively preparing the DNA to single stranded material.

Nucleic acid-based diagnostic tests have the potential to improve patient treatment by providing faster and more specific diagnoses than many currently available tests, and interest in broader use of DNA-based diagnostic testing is on the rise. ZyGEM is committed to making nucleic acid-based diagnostic testing more widely available by developing technologies to improve genotyping by making the process simpler, faster and lower-cost. ZyGEM’s core DNA extraction technology can be easily adapted for use in a variety of diagnostic testing settings.

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